What Does Toxic Stress Do to Children?

March 9, 2021

Guests: Nadine Burke Harris

Dr. Nadine Burke Harris is a pediatrician and California's first surgeon general, known for pioneering research on adverse childhood experiences (ACEs) and toxic stress. She founded the Center for Youth Wellness and wrote The Deepest Well, translating ACE science into clinical screening and early intervention.

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About this episode

California surgeon general Dr. Nadine Burke Harris explains her pioneering research on adverse childhood experiences: chronic stress from abuse, neglect, or household dysfunction keeps children's stress hormones elevated, reshaping the amygdala and prefrontal cortex, eroding telomeres, and raising lifelong risks of heart disease, depression, and early death. She calls the finding as significant as germ theory and argues toxic stress is a treatable health condition — with nurturing caregivers and early intervention able to buffer its effects — and draws out implications for incarceration, meritocracy, child allowances, and mental-health parity. Turning to California's pandemic response, Burke Harris defends a simple, equity-focused vaccine rollout: because Covid concentrates in the poorest quartiles, she argues, targeting disadvantaged communities with community partners is not just fair but the fastest route to reopening, even as she worries Texas-style premature reopenings could invite new surges.

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